Solid state chemistry is the study of the synthesis, crystal structure, and properties of solid phase materials. This area of inquiry and analysis is particularly relevant to explore the properties of oral solid dosage formulations.
In the graph provided below, the six pillars of solid state chemistry are illustrated with subcategories included to give further understanding of what solid state chemistry encompasses. Alcami fields this combined experimental and analytical capability through its own Center of Excellence (CoE) for solid state chemistry and crystallization, which is located in its active pharmaceutical ingredient (API) development facility in Weert, Netherlands.
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Edwin Aret holds a PhD in solid state chemistry from Radboud University Nijmegen, the Netherlands. He has nearly 20 years of experience supporting every facet of the pharmaceutical development cycle, from discovery to commercialization, covering small molecules, drug substance, and drug product. Edwin’s in-depth expertise includes crystallization, form selection, stability studies, solubility determination, bioavailability, and crystal habit optimization. Edwin is currently the principal scientist for solid state chemistry at Alcami.
Bianca van Bree
Bianca van Bree earned her PhD in biomedical sciences from Maastricht University, the Netherlands. She has over six years of experience in the pharmaceutical development industry. She started her career as a molecular biology research and development scientist, and advanced into project management. Her expertise is in managing pharmaceutical ingredients and biomedical device projects from research phase to early phase clinical trials. Bianca joined Alcami in 2018 as a project manager.