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SCIENTIST SPOTLIGHT: September 2017

pictureCMW.jpgName: Chris Witzigmann, PhD
Alcami Site: Germantown, WI

How long have you been with Alcami?

I joined Alcami in August of 2016.

What is your role? 
I am a Scientist in Chemical Research & Development at Alcami's Germantown, WI site.

What is the most rewarding part of your job?
Solving complex problems and translating the solutions from small scale work in R&D to the manufacturing scale.  Knowing that our work improves the efficiency and, most importantly, the quality of the APIs that we produce is very rewarding.

What are your team’s latest achievements?

Completing the first proof-of-concept continuous flow project in Alcami. 

How do you see those accomplishments affecting the pharmaceutical industry?
Continuous flow chemistry allows for multi-kilogram manufacturing with a much smaller manufacturing footprint, giving a huge potential for savings in catalyst, solvent and waste.  As an example, the project I worked on could save more than $2 million dollars per year by replacing an expensive rare metal catalyst with nickel, an inexpensive and common metal. Additional benefits include being able to re-use the catalyst, as opposed to the current process in which the catalyst is discarded as waste. Overall we’ve designed a more efficient and greener process and look forward to the implementation of the technologies necessary to move this from proof-of-concept R&D work to a full-fledged continuous manufacturing process!

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