API Manufacturing

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Pharmaceutical contract manufacturing services aligned to support the entire lifecycle

Alcami’s US API manufacturing center is housed in a state-of-the-art cGMP facility with 70 cubic meters of capacity. The site has all of the capabilities required to provide API clinical and commercial manufacturing services. The facility has a wide range of technologies including plant scale hydrogenation and cryogenics (-90C).

Alcami’s Germantown, Wisconsin facility features:
  • Reactors:
    • 4 x 2000 Gal GLS
    • 2 x 1500 Gal 316 SS
    • 4 x 1000 Gal GLS
    • 2 x 1000 Gal 316 SS
    • 1 x 500 Gal GLS
    • 2 x 500 Gal 316 SS
  • Cryogenic Vessel:
    • 1 x 500 Gal 316 SS
    • 1x 1000 Gal SS work up
  • Hydrogenation Vessels:
    • 1 x 500 Gal Hastelloy
    • 1 x 1000 Gal
  • Solvent Tank Farm
    • 5 x 8000 Gal Solvents
    • 4 x 8000 Gal Waste
  • Separation Equipment:
    • 2 x 800 mm Kraus Maffei Horizontal Peeler Centrifuges
  • Drying Equipment:
    • 2 x 800 Liter Kraus Maffei  Agitated Cone Dryers
    • Stokes 438 Tray dryer
    • 3 x 4 m2 SS 316 AFD with glove box
    • 1.4 m2 Hastelloy AFD with glove box
    • Therminol Single Fluid System (-30 to 150oC)
    • Cryo to -100oC
    • <20 mm Hg Vacuum
    • PLC control with data acquisition
    • Fully validated